| Tesis Doctorales de la Universidad de Alcalá |
| USE OF ANTIDEPRESSANTS AND THE RISK OF ACUTE MYOCARDIAL INFARCTION, AND NON-CARDIOEMBOLIC ISCHEMIC STROKE: TWO NESTED CASE-CONTROL STUDIES IN A PRIMARY HEALTH CARE DATABASE | | Autor/a | Fattouh Rajab, Rasha | | Departamento | Cirugía, Ciencias Médicas y Sociales | | Director/a | Bolumar Montrull, Francisco | | Codirector/a | Abajo Iglesias, Francisco José de | | Fecha de defensa | 11/03/2022 | | Calificación | Sobresaliente Cum Laude | | Programa | Epidemiología y Salud Pública (RD 99/2011) | | Mención internacional | No | | Resumen | 1year), sex, age
(<70, ¿70 years old) and background vascular risk in both AMI and non-cardioembolic IS.
Conclusions:
The first study suggests that current use of antidepressants interfering selectively with the reuptake of serotonin, and those antagonizing the 5-HT2A receptor, are associated with a decrease in AMI risk and should be the antidepressants of choice in patients at cardiovascular risk. The second study showed that use of SSRIs was not associated with an increased risk of non- cardioembolic ischemic stroke. On the contrary, as compared to other antidepressants, SSRIs appeared to be protective. |
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